Mutational analysis of the tobacco mosaic virus 5′-leader for altered ability to enhance translation
نویسندگان
چکیده
منابع مشابه
The 5'-leader of tobacco mosaic virus promotes translation through enhanced recruitment of eIF4F.
The 5'-leader sequence (called Omega) of tobacco mosaic virus (TMV) functions as a translational enhancer in plants. A poly(CAA) region within Omega is responsible for the translation enhancement and serves as a binding site for the heat shock protein, HSP101, which is required for the translational enhancement. Genetic analysis of the HSP101-mediated enhancement of translation from Omega-conta...
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15 صفحه اولMutational analysis of the cowpea mosaic virus movement protein.
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متن کاملIdentification and characterization of the functional elements within the tobacco etch virus 5' leader required for cap-independent translation.
Translation in plants is highly cap dependent, and the only plant mRNAs known to naturally lack a cap structure (m(7)GpppN) are viral in origin. The genomic RNA of tobacco etch virus (TEV), a potyvirus that belongs to the picornavirus superfamily, is a polyadenylated mRNA that is naturally uncapped and yet is a highly competitive mRNA during translation. The 143-nucleotide 5' leader is responsi...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1988
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/16.3.883